pentobarbital will minimize the extent or effect of saxagliptin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Not known.pentobarbital will increase effects of ifosfamide by impacting hepatic enzyme CYP2B6 metabolism. Use Caution/Monitor. Coadministration of ifosfamide with CYP2B6 inducers might raise metabol