pentobarbital will minimize the extent or effect of saxagliptin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Not known.
pentobarbital will increase effects of ifosfamide by impacting hepatic enzyme CYP2B6 metabolism. Use Caution/Monitor. Coadministration of ifosfamide with CYP2B6 inducers might raise metabolism of ifosfamide to its metabolite. Monitor for improved effects/toxicities if put together with CYP2B6 inducers.
Use Caution/Watch. CYP3A4 inducers may possibly increase the metabolism of clopidogrel to its Lively metabolite. Keep an eye on people for likely boost in antiplatelet effects when CYP3A4 inducers are applied in combination with clopidogrel
pentobarbital will decrease the level or impact of finasteride by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Mysterious.
pentobarbital will lower the level or influence of etravirine by influencing hepatic enzyme CYP2C9/ten metabolism. Use Warning/Monitor.
fentanyl intranasal and pentobarbital both of those improve sedation. Stay clear of or Use Alternate Drug. Restrict use to clients for whom alternate remedy possibilities are inadequate
With therapeutic doses of TCAs, barbiturates increase metabolism and reduce blood concentrations of TCAs.
pentobarbital will boost the degree or effect of clopidogrel by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will lower the extent or effect of venetoclax by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
Therapy ought to be administered with warning, if whatsoever, to clients who are mentally frustrated, have suicidal tendencies, or record of drug abuse
pentobarbital will lower the extent or result of fentanyl transdermal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Carefully. Coadministration of fentanyl with CYP3A4 inducers could lead to the lessen in fentanyl plasma concentrations, deficiency of efficacy or, potentially, growth of a withdrawal syndrome inside of a get more info affected person who has made Actual physical dependence to fentanyl.
pentobarbital will lower the extent or impact of felodipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will reduce the level or impact of parecoxib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unfamiliar.
pentobarbital will lower the level or influence of mifepristone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. CYP3A4 inducers have not been analyzed, coadministration not advised by company